Infections that involve a joint replacement are a difficult problem to treat. Most patients who incur this unusual complication presents to their orthopedic surgeon who may only treat one or two of these problems a year. To that end, the OrthoCarolina Hip and Knee Center has established a Periprosthetic Joint Infection Center to serve those patients with this unusual complication. Our Periprosthetic Joint Infection Center treats more of these patients than anyone in the Southeast. We do research on a national level to determine the best types of procedures to successfully treat this complication.